The blaze was reported just before 1:40 p.m. Sunday at Leisureland Mobile Village at 1951 47th St., according to the San Diego Fire-Rescue Department.
It was sparked by a cigarette left in a trash can, department spokesman Maurice Luque told The San Diego Union-Tribune.
Firefighters took less than 15 minutes to put out the fire before finding the woman underneath some wall paneling, he said. Her name was withheld pending positive identification by the county coroner's office.
Damage to the mobile home and its content was estimated at $100,000.
A gas line break in downtown has prompted area businesses to evacuate. The break was reported around 1 p.m. and is located near Fifth Avenue and E Street.
One week ago as diners packed restaurants in a Kearny Mesa a shooting broke out in the parking lot of a strip mall on Convoy Street.
Skies across San Diego County are mostly clear and will stay that way through the early Saturday. This will result in another night of tumbling temps into early Saturday morning.
The first phase of the city of San Diego's ordinance banning polystyrene foam and single-use plastics will go into effect on Saturday.
A pothole here. A pothole there. The City of San Diego says it has seen a spike in reports of potholes due to recent winter storms.
Hundreds of San Diego State students are dancing the night away Friday as part of a 15-hour dance marathon which will end Saturday morning.
The owner of an Ocean Beach sandwich shop is sharing surveillance video of a man he says stole the employees tip jar.
The National Weather Service on has issued a frost advisory from 10 p.m., Friday to 9 a.m., Saturday for the inland valleys of San Diego.