The parade, now in its 18th year, will also feature a procession of 22 giant balloon characters, including Mighty Mouse, Clifford, Horton the Elephant and Mr. Potato Head, organizers said.
The festivities get under way at 9 a.m. in downtown along Harbor Drive on the San Diego Bay waterfront.
The spectacle is part of the festivities surrounding the Pacific Life Holiday Bowl, which begins at 5 p.m. Tuesday at Qualcomm Stadium. The game will pit the University of Oregon Ducks against the Oklahoma State University Cowboys.
Gusty winds are expected to sweep through San Diego County starting Monday and cause potentially dangerous driving conditions through Wednesday, meteorologists said.
A fire that started in a garage badly damaged a home in Scripps Ranch on Sunday morning, a fire official said.
A seemingly wayward hot air balloon landed in a Ramona field on Sunday much to the surprise of on-lookers.
Several residents of an apartment complex in El Cajon were displaced Sunday after a driver accidentally crashed into their building.
An allegedly-intoxicated driver crashed down an embankment after trying to evade a pursuing sheriff's deputy Saturday night.
San Diegans are going online to raise money to help make ends meet amid a partial government shutdown prolonged by a impasse over President Trump's demand for a wall along the U.S.-Mexico border.
Waterfront Park in downtown San Diego played host to thousands of people demonstrating in the third annual Women's March, which also took place in dozens of other cities across the country.