Police are looking for a suspect who caused a chain-reaction accident in La Mesa Thursday night on Interstate 8 near Baltimore Drive.
Witnesses say a Ryder moving truck full of furniture was traveling west, when it was hit by a red or maroon compact car.
The truck crossed over into oncoming traffic and hit a pickup head on.
"The force of the collision was so great that it caused the truck to go over the top of the center divide wall," said Brian Pennings with the California Highway Patrol. "Both drivers sustained fatal injuries."
Both drivers were 32-year-old.
Police say the hit-and-run driver will face charges once that person is caught.
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