The shooting occurred just before 2 a.m. Sunday at the Paradise Hookah Lounge on Paradise Valley Road.
A sheriff's lieutenant said the two shooting victims arrived at Grossmont Hospital. One had a shoulder wound and the other had been shot in the abdomen.
Both are expected to survive.
A third shooting victim arrived at the hospital, but it was not clear whether he was shot at the lounge.
No arrests have been made in connection with the shooting.
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