People.com reports that 31-year-old Jennifer Meyer gave birth to a baby boy on Friday. Maguire publicist Kelly Bush on Sunday confirmed the birth but gave no other details.
Meyer gave birth to the couple's daughter, Ruby Sweetheart Maguire, more than two years ago.
The 33-year-old Maguire and Meyer met in 2003 and were married in 2007.
Meyer is the daughter of Ron Meyer, president and chief operating officer of Universal Studios.
Maguire's other screen credits include "Seabiscuit" and "Wonder Boys."
Copyright 2009 The Associated Press.