Winfrey will bid Dr. Mehmet (meh-MEHT') Oz farewell on Tuesday's episode of her talk show. His program, "The Dr. Oz Show," is to debut Sept. 14.
Oz has been featured on Winfrey's show for five years and 55 episodes. He would often offer diet tips or discuss life-threatening diseases.
Tuesday's show ends with Oz and Winfrey raising a champagne toast.
According to Oz's biography on Oprah.com, the best-selling author and heart surgeon is a surgery professor at Columbia University and directs the Cardiovascular Institute and Complementary Medicine Program at New York-Presbyterian Hospital.
Copyright 2009 The Associated Press.