Both victims were pedestrians struck by cars late on Saturday night in separate incidents on Cardiff-by-the-Sea and Ramona.
This year's Christmas reporting period began at 6 p.m. Wednesday and is longer than the 2007 holiday, so there are no comparable figures, according to CHP Officer Rob Sanchez.
There have also been 95 arrests for drunken driving, nearly half on Saturday or early Sunday morning, Sanchez said.
Statewide, there have been 26 fatalities and 1,536 DUI arrests, he said.
The statistics for fatalities cover all law enforcement jurisdictions. The DUI total only reflects arrests made by CHP officers.