SAN DIEGO (AP) - Adrian Gonzalez matched his career high with four hits, including a homer, and scored the winning run with two outs in the 10th inning as the San Diego Padres beat the Seattle Mariners 4-3 Thursday to end their major league-record interleague losing streak at 13.

Gonzalez doubled off Miguel Batista (3-2) and scored on Kevin Kouzmanoff's single to left, beating the throw from Endy Chavez. Gonzalez also homered in the sixth, his first in 13 games, to tie Albert Pujols for the major league lead with 23.

Heath Bell (3-1) threw two innings for the win.

The Padres had lost 10 straight games to Seattle in San Diego, and 16 of 20 overall against the Mariners.

Seattle's Franklin Gutierrez hit two homers for the first time in his career, both off Josh Geer. Gutierrez has six this season.

He homered into the sand play area beyond the fence in right-center with one out in the fourth to tie the game at 2. His second shot landed in the balcony on the second level of the Western Metal Supply Co. brick warehouse in the left-field corner with one out in the sixth to give the Mariners a 3-2 lead.

Gonzalez tied the game with his homer to straightaway center leading off the bottom half. Gutierrez, the center fielder, ran back to the fence and leaped for the ball but it hit off the back of his glove and went over. Gutierrez slapped his glove in frustration.

It was Gonzalez's first home run since June 2 against Philadelphia.

Ken Griffey Jr. hit an RBI double for the second straight game, giving Seattle a 1-0 lead in the first. San Diego went ahead in the bottom half on David Eckstein's RBI double and Gonzalez's RBI single.

Geer allowed three runs and six hits in six innings, struck out six and walked none.

Brandon Morrow made his second straight start for Mariners left-hander Erik Bedard, on the disabled list with shoulder inflammation. Morrow lasted four innings, allowing two runs and five hits with six strikeouts and one walk.

NOTES: Chris Young will be placed on the 15-day disabled list Friday due to inflammation in his right shoulder, meaning the Padres' top two pitchers will be out of action. San Diego ace Jake Peavy went on the DL on Saturday, a day after learning he would be sidelined at least a month because of a strained tendon behind his right ankle. ... Seattle placed 2B Jose Lopez on the bereavement list and called up INF Chris Woodward from the minors. Lopez, who leads the team with 42 RBIs, left the club before Thursday's game to return to his native Venezuela because his sister is seriously ill. Mariners manager Don Wakamatsu doesn't expect Lopez back for at least five days. ... Mariners 1B Mike Carp had his first big league start, hit and run. He singled with one out in the first and scored on Griffey's double.

Copyright 2009 The Associated Press.